As the average length of the human life span continues to increase, the likelihood of an individual developing a neurodegenerative disease also increases. Thus, there is a need to understand the aging process and its role in the development of age-onset disorders such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. Research in the Van Raamsdonk Laboratory is focused on gaining insight into the aging process and the pathogenesis of such diseases. In addition to the obvious benefit to the individual, this work has great potential benefits for society by decreasing health care costs and helping to maintain productivity and independence to a later age.
To use genetic models to gain insight into the aging process and the pathogenesis of neurodegenerative disease and to use this knowledge to improve healthspan and develop effective treatments for disease.